James) have designed a new mathematical model to determine radiation doses delivered during several conditions such as treating cancer patients. The study is highlighted in the journal Science Translational Medicine.Usually, radiation doses are delivered, in small concentrations, to cancer patients on daily basis for several weeks. Radiation oncologists are used to determine the schedules for the fractionated, low-dose radiation courses applying a mathematical model named the linear-quadratic (LQ) Model. However, this model does not provide accuracy when used on high radiation doses. Dr. Nina Mayr, professor of radiation oncology at the OSUCCC-James, and the co-author of the study, explained "Unfortunately the LQ Model doesn't work well for high-dose radiation therapy. Our study resolves this problem by modifying the current method to develop the Generalized LQ (gLQ) Model that covers all dose levels and schedules." Dr.Mayr added that Generalized LQ offers new options for planning radiation doses and schedules used during recent procedures such as radiosurgery, stereotactic radiation therapy and high-dose brachytherapy techniques....
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