Two-photon Microscopy Technique To Monitor Immune Cells In Lung, Study.

According to UCSF-led study in mice, researchers improved a way to equalize living lung tissue for screening without disrupting the normal function of the organ. This way was used for the first time and it permitted the researching team to observe both the unfolding events in the immune response during lung injury and the live interaction of living cells in the context of their environment. The authors mentioned that, the capability to screen the lung and other organs with minimum tissue disruption permits scientists to look deeper into many physiological aspects of injury and diseases for instance, cancer and diabetes. 

Senior author Max Krummel, PhD, UCSF associate professor of Pathology, whose lab improved the recent screening technique for viewing minute details of cellular interaction in tissues, reported "The nature of disease is complex, so if scientists can observe in real-time what's happening in tumors or immune responses as they occur, we can find new ways to intervene. We figured out a method for holding cells still enough to image them without interrupting their normal processes. This enabled us to observe cellular events as they happen naturally rather than the usual way, which is to stop the motion of cellular processes in order to photograph them."
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Two-photon Microscopy Technique To Monitor Immune Cells In Lung, Study.